Oral mucosal lesions in patients with SARS-CoV-2 infection. Report of four cases. Are they a true sign of COVID-19 disease?

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dc.contributor.authorCruz Tapia, Roberto Onner
dc.contributor.authorPeraza Labrador, Alberto Jose
dc.contributor.authorGuimarães, Douglas Magno
dc.contributor.authorMatos Valdez, Luciano Hermios
dc.date.accessioned2020-09-23T13:30:47Z
dc.date.available2020-09-23T13:30:47Z
dc.date.issued2020
dc.description.abstractenglishBackground Vesiculobullous and macular lesions in the oral mucosa have been reported in patients positive for SARS‐CoV‐2 infection. Nonetheless, the significance and physiopathology of oral manifestations have not been clearly established in the clinical progression or outcome of the infection. Aim To describe the clinico‐pathological oral mucosal lesions in four patients with confirmed SARS‐CoV‐2 infection. Methods and Results Four patients with COVID‐19 disease and confirmed by polymerase chain reaction (PCR) presented angina bullosa hemorragica‐like lesion, vascular disorder, and nonspecific stomatitis, one patient with histological analysis demonstrated perivascular reactive lymphocitic infliltrate, focal capillary thrombosis, and hemorrhage. According to the discrimination of other local and systemic conditions and the synchronous onset of oral and systemic symptoms, the diagnosis of oral lesions probably associated with COVID‐19 was established. Conclusion Infection with SARS‐CoV‐2 may result in oral manifestations with various clinical presentations, which presumably support the hypothesis of thrombi formation and vasculitis; nevertheless, these findings need more evidence and a long‐term follow up of patients to accurately establish the significance of the oral mucosa affection in the COVID‐19 disease.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/scd.12520
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1754-4505
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/4133
dc.language.isoeng
dc.publisherWiley-Blackwellspa
dc.publisher.journalSpecial care in dentistryspa
dc.relation.ispartofseriesSpecial care in dentistry, 1754-4505. 2020spa
dc.relation.urihttps://onlinelibrary.wiley.com/doi/full/10.1111/scd.12520
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020-09-03
dc.rights.localAcceso abiertospa
dc.subject.keywordsCase reportsspa
dc.subject.keywordsCOVID-19spa
dc.subject.keywordsOral manifestationsspa
dc.subject.keywordsSARS-CoV-2spa
dc.titleOral mucosal lesions in patients with SARS-CoV-2 infection. Report of four cases. Are they a true sign of COVID-19 disease?spa
dc.title.translatedOral mucosal lesions in patients with SARS-CoV-2 infection. Report of four cases. Are they a true sign of COVID-19 disease?spa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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