Drug reaction with eosinophilia and systemic symptoms (DRESS) and multiple organ dysfunction syndrome (MODS): one more reason for a new effective treatment against leishmaniasis

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dc.contributor.authorCuestas, Daniel
dc.contributor.authorForero, Yency
dc.contributor.authorGalvis Diaz, Ingrid Johanna
dc.contributor.authorPeñaranda, Elkin
dc.contributor.authorCortes, Carolina
dc.contributor.authorMotta Beltrán, Adriana
dc.contributor.authorMora, Sergio Alexander
dc.contributor.authorPérez, Carlos
dc.contributor.authorVelasquez, Oscar
dc.contributor.authorPuentes, José
dc.contributor.orcidMotta, Adriana [0000-0002-1924-1256]
dc.contributor.orcidMotta Beltrán, Adriana [0000-0002-1924-1256]
dc.contributor.orcidMotta Beltrán, Adriana [0000-0002-1924-1256]
dc.date.accessioned2020-05-18T04:53:29Z
dc.date.available2020-05-18T04:53:29Z
dc.date.issued2018
dc.description.abstractenglishIntroduction Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe drug‐induced reaction associated with eosinophilia and systemic manifestations. Anticonvulsants, sulfonamides, and antivirals are the most related and described drugs in DRESS syndrome. Methods and case We present a case of severe multiple organ dysfunction syndrome (MODS) with the risk of death associated with DRESS syndrome due to antileishmanial pentavalent antimonial drug and its simultaneous toxicity. Consequently, a comprehensive review of the main clinical problems and comparative discussion of both clinical conditions was made. Discussion The overlap of DRESS syndrome and antileishmanial pentavalent antimonial drug toxicity can be life‐threatening. Both conditions represent a true clinical, diagnostic, and therapeutic challenge. We exposed specific clinical and laboratory results with rare occurrence. Conclusion Any physician and dermatologists should keep in mind the broad spectrum of clinical manifestations and laboratory findings associated with the use of pentavalent antimonial drugs. The clinical suspicion, an early diagnosis, and aggressive treatment are essential to prevent complications and death.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/ijd.14126
dc.identifier.issn0011-9059
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2894
dc.language.isoeng
dc.publisherWileyspa
dc.publisher.journalInternational Journal of Dermatologyspa
dc.relation.ispartofseriesInternational Journal of Dermatology, 0011-9059, Vol 57, Num 11, 2018, pag 1304-1313spa
dc.relation.urihttps://onlinelibrary.wiley.com/doi/abs/10.1111/ijd.14126
dc.rights.creativecommons2018
dc.rights.localAcceso cerradospa
dc.subject.decsSíndrome de hipersensibilidad a medicamentosspa
dc.subject.decsInsuficiencia multiorgánicaspa
dc.subject.decsLeishmaniasis -- Tratamientospa
dc.titleDrug reaction with eosinophilia and systemic symptoms (DRESS) and multiple organ dysfunction syndrome (MODS): one more reason for a new effective treatment against leishmaniasisspa
dc.title.translatedDrug reaction with eosinophilia and systemic symptoms (DRESS) and multiple organ dysfunction syndrome (MODS): one more reason for a new effective treatment against leishmaniasisspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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