Utilidad del diagnóstico visual y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes permanentes

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dc.contributor.advisorMartignon Biermann, Stefania
dc.contributor.advisorMartínez Mier, E. Ángeles
dc.contributor.authorCuevas Espinosa, Diana Milena
dc.date.accessioned2023-03-03T19:18:36Z
dc.date.available2023-03-03T19:18:36Z
dc.date.issued2016
dc.description.abstractLa fluorosis dental, defecto del desarrollo del esmalte, es un problema de salud pública en Colombia. Su diagnóstico se basa, comúnmente, en hallazgos visuales; aunque recientemente se ha diagnostico con base a tecnologías de imágenes. El índice TFI se utiliza para el diagnóstico visual de la fluorosis y se ha validado frente a los estándares de oro microscopía de luz polarizada (PLM) y microrradiografía (TMR). El propósito de este estudio fue determinar la utilidad del diagnóstico visual y por cuantificación de luz fluorescente a través de imágenes (QLF) frente a la microscopía de luz polarizada (PLM) y la microrradiografía (TMR) en fluorosis leve y moderada en dientes permanentes. A partir de 300 dientes permanentes sanos y con fluorosis, se seleccionaron 148 sobre imágenes estereomicroscópicas y se agruparon en sanos, fluorosis leve (TFI 1-2) y moderada (TFI 3-4). Posteriormente se valoró fluorosis dental con: -QLF convencional (Análisis de superficie) y QLF ROI (Región de interés) sobre imágenes de fluorescencia obtenidas de la superficie estibular y determinando A (área), ΔF (pérdida de fluorescencia) y ΔQ (volumen de la lesión); -TMR sobre secciones longitudinales (80-120µm) en ROI, determinando ΔZ (pérdida mineral), LD (profundidad de la lesión), SS (capa subsuperficial); -PLM, sobre las secciones embebidas en agua a X5, clasificando histológicamente en sanos, fluorosis leve y moderada. La muestra total correspondió a 137 dientes, (Exclusión: 11 dientes): TFI-0: n=18, TFI-1: n=37, TFI-2: n=36, TFI-3: n=34, TFI-4: n=12. Las correlaciones fueron: -fuerte entre TFI y PLM (kappa ponderado 0.82); nula entre QLF y TMR (S:rho=0.02, p=0.79;ROI:rho=0.01, p=0.84); positiva entre QLF y PLM,mayor para ROI (KTau=0.51; p≥0.001); la mayor correlación fue para la variable ΔF ROI de umbral 5; positiva entre QLF y TFI,mayor para ROI (KTau=0.53, p≥0.001); la correlación más fuerte fue para la variable ΔF ROI de umbral 5.spa
dc.description.abstractenglishDental fluorosis, a developmental enamel defect has been considered a public health problem in Colombia. Its diagnosis has been commonly based on visual findings; however, imaging techniques have also been recently used. The TFI index, which has been used for visual diagnosis of dental fluorosis, has been validated against the gold standards: Polarized Light Microscopy (PLM) and Microradiography (TMR). The purpose of this study was to determine the validity of the visual diagnosis with TFI and Quantitative Light-induced Fluorescence (QLF) by comparing it to Polarized light microscopy (PLM) and microradiography (TMR) in permanent teeth with mild and moderate fluorosis. Starting with 300 permanent teeth, 148 samples were selected using stereomicroscopic images and were classified as sound, mild fluorosis (TFI 1-2) and moderate fluorosis (TFI 3-4). Later, dental fluorosis was assessed by means of: -conventional QLF (surface analysis) and QLF ROI (Region of Interest) Fluorescence images were obtained of the vestibular surfaces and were used to determine A (area), ΔF (fluorescence loss) and ΔQ (lesion volume). -TMR: Over longitudinal sections (80-120 µm) in ROI, ΔZ (mineral loss), LD (lesion depth) and SS (subsurface layer) were determined. –PLM: sections were histologically classified in water immersion at 5X, as sound, mild fluorosis and moderate fluorosis. The total sample consisted of 137 teeth (excluding 11 teeth): TFI-0: n=18, TFI-1: n=37, TFI-2: n=36, TFI-3: n=34, TFI-4: n=12. The correlations were: positive between TFI and PLM (weighted kappa 0.82); null between QLF and TMR (S:rho=0.02, p=0.79;ROI:rho=0.01, p=0.84); positive between QLF and PLM,greater for ROI (KTau=0.51, p≥0.001);, the greatest correlation was for the variable ΔF ROI of threshold 5 positive between QLF and TMR,greater for ROI(KTau=0.53, p≥0.001), the strongest correlation was for the variable ΔF ROI of threshold 5.eng
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Ciencias Odontológicasspa
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/10101
dc.language.isospa
dc.publisher.facultyFacultad de Odontologíaspa
dc.publisher.grantorUniversidad El Bosquespa
dc.publisher.programMaestría en Ciencias Odontológicasspa
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dc.rights.accessrightsinfo:eu-repo/semantics/closedAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_14cb
dc.rights.localAcceso cerradospa
dc.subjectFluorosis dentalspa
dc.subjectDiagnósticospa
dc.subjectTFIspa
dc.subjectDientes permanentesspa
dc.subjectHistologíaspa
dc.subjectFluorescenciaspa
dc.subjectMicrorradiografíaspa
dc.subject.keywordsEnamel fluorosisspa
dc.subject.keywordsDiagnosisspa
dc.subject.keywordsPermanent teethspa
dc.subject.keywordsHistologyspa
dc.subject.keywordsFluorescencespa
dc.subject.keywordsMicroradiographyspa
dc.subject.nlmWU 100
dc.titleUtilidad del diagnóstico visual y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes permanentesspa
dc.title.translatedUsefulness of visual (TFI) and QLF diagnosis versus PLM and TMR in mild and moderate fluorosis in permanent teethspa
dc.type.coarhttps://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttps://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesis/Trabajo de grado - Monografía - Maestríaspa

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Utilidad del diagnóstico visual y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes permanentes
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Utilidad del diagnóstico visual y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes permanentes
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