A comparative analysis of the bronchodilatador response measured by impulse oscillometry and spirometry in asthmatic children living at high altitude

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dc.contributor.authorRamirez, Oscar
dc.contributor.authorAlvarez, Ivan
dc.contributor.authorAristizabal-Duque, Ricardo
dc.contributor.authorVillamil Osorio, Milena
dc.contributor.authorSossa-BriceƱo, Monica P.
dc.contributor.authorRodriguez-Martinez, Carlos E.
dc.date.accessioned2021-02-05T18:42:28Z
dc.date.available2021-02-05T18:42:28Z
dc.date.issued2020
dc.description.abstractenglishAlthough the assessment of a bronchodilator response (BDR) is a routine and important procedure when performing lung function tests, comparisons between spirometric and oscillometric BDRs in asthmatic children living at high altitude have not been previously reported. The aim of the present study was to compare spirometric and oscillometric BDRs in children living at high altitude, and to identify independent predictors of spirometric and oscillometric BDRs. Between January and December, 2015, asthmatic children aged between 5 and 17 years old performed impulse oscillometry (IOS) and spirometry during the same visit before and after albuterol administration. The data were analyzed, and children were classified into those positive for oscillometric BDR only, those positive for spirometric BDR only, those positive for both BDRs, and those negative for both BDRs. Ninety-three asthmatic children (56 boys, 37 girls), with a median (IQR) age of 11 (8-13) years, made up the study population. Among the total of 93 participants, 13 (14.0%), 4 (4.3%), 0 (0%), and 76 (81.7%) were positive for spirometric BDR only, positive for oscillometric BDR only, positive for both BDRs, and negative for both BDRs, respectively. Age and baseline lung function were identified as significant predictors of positive spirometric BDR. The present study shows poor concordance between positive spirometric and oscillometric BDRs, with a greater proportion of patients with a spirometric BDR when compared to those with positive oscillometric BDR. Additionally, age and baseline lung function are useful for predicting spirometric BDR results.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1080/02770903.2020.1801722
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1532-4303
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5260
dc.language.isoeng
dc.publisherTaylor & Francisspa
dc.publisher.journalJournal of Asthmaspa
dc.relation.ispartofseriesJournal of Asthma, 1532-4303, 2020 p. 1-7spa
dc.relation.urihttps://www.tandfonline.com/doi/abs/10.1080/02770903.2020.1801722
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020-08-04
dc.rights.localAcceso abiertospa
dc.subject.keywordsAsthmaspa
dc.subject.keywordsBronchodilator responsespa
dc.subject.keywordsChildhoodspa
dc.subject.keywordsImpulse oscillometryspa
dc.subject.keywordsReversibilityspa
dc.subject.keywordsSpirometryspa
dc.titleA comparative analysis of the bronchodilatador response measured by impulse oscillometry and spirometry in asthmatic children living at high altitudespa
dc.title.translatedA comparative analysis of the bronchodilatador response measured by impulse oscillometry and spirometry in asthmatic children living at high altitudespa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtĆ­culo de revista

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