Simultaneous infection with enterobacteriaceae and pseudomonas aeruginosa harboring multiple carbapenemases in a returning traveler colonized with candida auris
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Author
Ayesha, Khan
Wanger, Audrey
Ostrosky-Zeichner, Luis
Date
2020Published in
American Society for Microbiology Journals,1098-6596, Vol.64, Nro. 2, 2020, p. 1-6
Published for
American Society for Microbiology
Source's URL
https://aac.asm.org/content/64/2/e01466-19Citación
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Abstract
We report our clinical experience treating a critically ill patient with polymicrobial infections due to multidrug-resistant Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa in a 56-year-old woman who received health care in India and was also colonized by Candida auris. A precision medicine approach using whole-genome sequencing revealed a multiplicity of mobile elements associated with NDM-1, NDM-5, and OXA-181 and, supplemented with susceptibility testing, guided the selection of rational antimicrobial therapy.
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