Further validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening center

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dc.contributor.authorEmura, Fabian
dc.contributor.authorSaito, Yutaka
dc.contributor.authorTaniguchi, Makoto
dc.contributor.authorFujii, Takahiro
dc.contributor.authorTagawa, Kazumi
dc.contributor.authorYamakado, Minoru
dc.date.accessioned2021-02-04T21:18:46Z
dc.date.available2021-02-04T21:18:46Z
dc.date.issued2007
dc.description.abstractenglishThe accuracy of conventional colonoscopy to differentiate neoplastic and non‐neoplastic polyps is limited, justifying a biopsy for histologic analysis. Magnifying chromocolonoscopy has emerged as the best tool available for differentiating adenomatous and hyperplastic polyps during colonoscopy; however, magnifying endoscopes are rarely used in endoscopy units. This study aimed to further validate the effectiveness of magnifying chromocolonoscopy in the diagnosis of neoplastic colorectal polyps in a screening center. Five hundred average‐risk subjects were randomly divided into two groups: a magnifying chromocolonoscopy group and a conventional chromocolonoscopy group, each of 250 subjects. Lesions were analyzed according to Kudo's classification of pit pattern (types I–V) and additionally subdivided into non‐neoplastic (types I–II) and neoplastic (types III–V). Lesions judged as neoplastic were resected and those judged as non‐neoplastic were left in situ. Only lesions ≤10 mm were included in the study. Resected lesions were analyzed with histopathological examination. The overall accuracy of magnifying chromocolonoscopy for differentiating neoplastic lesions (95%, 135 of 142), was significantly higher than that of conventional chromocolonoscopy (84%, 102 of 122; P < 0.01). The accuracy of magnifying chromocolonoscopy for differentiating neoplastic lesions ≤5 mm was 94% (135 of 142), whereas that of conventional chromocolonoscopy was only 78% (69 of 89; P < 0.001). Results were not affected by the macroscopic types. Magnifying chromocolonoscopy is superior to conventional chromocolonoscopy for the diagnosis of colorectal neoplastic lesions in the setting of a health testing center.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/j.1440-1746.2007.04975.x
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1440-1746
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5251
dc.language.isoeng
dc.publisherWileyspa
dc.publisher.journalJournal of Gastroenterology and Hepatologyspa
dc.relation.ispartofseriesJournal of Gastroenterology and Hepatology, 1440-1746, Vol. 22, Nro. 11, 2007 p. 1722-1727spa
dc.relation.urihttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1746.2007.04975.x
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2007-06
dc.rights.localAcceso abiertospa
dc.subject.keywordsChromoendoscopyspa
dc.subject.keywordsHealth screening centerspa
dc.subject.keywordsMagnifying colonoscopyspa
dc.subject.keywordsNeoplastic lesionspa
dc.subject.keywordsNon‐neoplastic lesionspa
dc.subject.keywordsScreening colonoscopyspa
dc.titleFurther validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening centerspa
dc.title.translatedFurther validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening centerspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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