Avances recientes en nanopartículas para el tratamiento del cáncer de mama: métodos de obtención, métodos de caracterización y perspectivas a futuro

Camargo Ortíz, Paula; Gamboa Rodríguez, Laura Juliana

Avances recientes en nanopartículas para el tratamiento del cáncer de mama: métodos de obtención, métodos de caracterización y perspectivas a futuro

dc.contributor.advisor	Velandia París, María Angélica
dc.contributor.author	Camargo Ortíz, Paula
dc.contributor.author	Gamboa Rodríguez, Laura Juliana
dc.date.accessioned	2025-05-16T20:58:41Z
dc.date.available	2025-05-16T20:58:41Z
dc.date.issued	2025-05
dc.description.abstract	El cáncer de mama es una enfermedad con gran prevalencia a nivel mundial y se caracteriza por el crecimiento anormal y descontrolado de las células epiteliales y mioepiteliales de la mama. Tradicionalmente, el tratamiento ha estado basado en quimioterapias convencionales, las cuales carecen de selectividad para las células cancerosas, afectando también a células sanas y generando efectos adversos. En los últimos años, la investigación ha avanzado en el desarrollo de sistemas basados en nanopartículas para la administración de fármacos antineoplásicos, con el propósito de mejorar la selectividad y eficacia del tratamiento. El presente trabajo revisa los avances en nanopartículas para el tratamiento del cáncer de mama en los últimos cinco años, incluyendo sus métodos de obtención y métodos de caracterización, con el fin de establecer sus ventajas frente a terapias convencionales y perspectivas a futuro en este campo de investigación.
dc.description.abstractenglish	Breast cancer is a disease with a high prevalence worldwide and is characterized by the abnormal and uncontrolled growth of epithelial cells and myoepithelial cells of the breast. Traditionally, treatment has been based on conventional chemotherapies, which lack selectivity for cancerous cells, affecting also healthy cells and generating adverse effects. In the last years, research has advanced in the development of systems based on nanoparticles for the administration of antineoplastic drugs, with the aim of improving the selectivity and efficacy of the treatment. This paper reviews the advances in nanoparticles for the treatment of breast cancer in the last five years, including their methods of obtaining and characterization methods, in order to establish their advantages over conventional therapies and future prospects in this field of research
dc.description.degreelevel	Pregrado	spa
dc.description.degreelevel	Químico Farmacéutico	spa
dc.format.mimetype	application/pdf
dc.identifier.instname	Universidad El Bosque	spa
dc.identifier.reponame	reponame:Repositorio Institucional Universidad El Bosque	spa
dc.identifier.repourl	repourl:https://repositorio.unbosque.edu.co
dc.identifier.uri	https://hdl.handle.net/20.500.12495/14377
dc.language.iso	es
dc.publisher.faculty	Facultad de Ciencias	spa
dc.publisher.grantor	Universidad El Bosque	spa
dc.publisher.program	Química Farmacéutica	spa
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dc.rights	Attribution-NonCommercial-ShareAlike 4.0 International	en
dc.rights.accessrights	info:eu-repo/semantics/openAccess
dc.rights.accessrights	https://purl.org/coar/access_right/c_abf2
dc.rights.local	Acceso abierto	spa
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject	Cáncer de mama
dc.subject	Nanopartículas
dc.subject	Quimioterapia
dc.subject	Terapia dirigida
dc.subject	Liberación controlada
dc.subject.ddc	615.19
dc.subject.keywords	Breast cancer
dc.subject.keywords	Nanoparticles
dc.subject.keywords	Chemotherapy
dc.subject.keywords	Targeted therapy
dc.subject.keywords	Controlled release
dc.title	Avances recientes en nanopartículas para el tratamiento del cáncer de mama: métodos de obtención, métodos de caracterización y perspectivas a futuro
dc.title.translated	Recent advances in nanoparticles for the treatment of breast cancer: procurement methods, characterization methods and future perspectives
dc.type.coar	https://purl.org/coar/resource_type/c_7a1f
dc.type.coarversion	https://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driver	info:eu-repo/semantics/bachelorThesis
dc.type.hasversion	info:eu-repo/semantics/acceptedVersion
dc.type.local	Tesis/Trabajo de grado - Monografía - Pregrado