Enfermedades reumatológicas en pacientes con hepatitis autoinmune en un hospital de cuarto nivel de Bogotá entre el 2013 al 2023

Vergara Cabra, Cathalina; Almánzar Cortés, Juan Sebastián

Enfermedades reumatológicas en pacientes con hepatitis autoinmune en un hospital de cuarto nivel de Bogotá entre el 2013 al 2023

dc.contributor.advisor	Quintana, Gerardo
dc.contributor.advisor	Sierra Arango, Fernando
dc.contributor.author	Vergara Cabra, Cathalina
dc.contributor.author	Almánzar Cortés, Juan Sebastián
dc.date.accessioned	2024-07-25T16:13:29Z
dc.date.available	2024-07-25T16:13:29Z
dc.date.issued	2024-07
dc.description.abstract	Introducción: La hepatitis autoinmune (HAI) es una enfermedad crónica inflamatoria del hígado de baja prevalencia a nivel global. En múltiples estudios se ha evaluado la coexistencia de esta entidad con enfermedades reumatológicas la cual es muy variable. El objetivo de este estudio es identificar la frecuencia de la coexistencia de enfermedades reumatológicas y hepatitis autoinmune en adultos que han sido atendidos durante 10 años en un hospital de cuarto nivel en Bogotá, Colombia. Materiales y métodos: Estudio observacional analítico de corte transversal en un único centro que incluyó pacientes mayores de 18 años de ambos sexos con diagnóstico de HAI por “score” simplificado ≥7 puntos, con historia clínica registrada en el Hospital Fundación Santa Fe de Bogotá entre enero de 2013 y diciembre 2023. Resultados: Un total de 66 pacientes cumplieron criterios de inclusión. El 36.4% de los pacientes presentaban una enfermedad autoinmune concomitante, siendo el síndrome de Sjögren, el lupus eritematoso sistémico y la enfermedad tiroidea autoinmune las de mayor prevalencia. Conclusión: La frecuencia de la coexistencia de hepatitis autoinmune con enfermedades reumatológicas en pacientes adultos es del 36.4% para la cohorte estudiada, encontrándose en el rango de lo ya reportado a nivel global, donde se ha descrito una prevalencia del 14 al 44%.
dc.description.abstractenglish	Introduction: Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease with low prevalence worldwide. The coexistence of this entity with rheumatic diseases has been evaluated in multiple studies and is highly variable. The objective of this study is to identify the frequency of coexistence of rheumatic diseases and autoimmune hepatitis in adults who have been treated for 10 years in a fourth-level hospital in Bogota, Colombia. Materials and methods: Analytical, observational, cross-sectional study in a single center that included patients over 18 years of age of both sexes with a diagnosis of AIH by simplified score ≥7 points, with a medical history registered at the Fundacion Santa Fe de Bogota in Bogota, Colombia between January 2013 and December 2023. Results: A total of 66 patients met inclusion criteria. 36.4% of patients had a concomitant autoimmune disease, with Sjögren's syndrome, systemic lupus erythematosus and autoimmune thyroid disease being the most prevalent. Conclusion: The frequency of coexistence of autoimmune hepatitis with rheumatic diseases in adult patients is 36.4% for the cohort studied, which is within the range of what has already been reported globally, where a prevalence of 14 to 44% has been described.
dc.description.degreelevel	Especialización	spa
dc.description.degreename	Especialista en Medicina Interna	spa
dc.description.sponsorship	Fundación Santa Fe de Bogotá
dc.format.mimetype	application/pdf
dc.identifier.instname	instname:Universidad El Bosque	spa
dc.identifier.reponame	reponame:Repositorio Institucional Universidad El Bosque	spa
dc.identifier.repourl	repourl:https://repositorio.unbosque.edu.co
dc.identifier.uri	https://hdl.handle.net/20.500.12495/12731
dc.language.iso	es
dc.publisher.faculty	Facultad de Medicina	spa
dc.publisher.grantor	Universidad El Bosque	spa
dc.publisher.program	Especialización en Medicina Interna	spa
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dc.rights	Atribución-NoComercial-CompartirIgual 4.0 Internacional	en
dc.rights.accessrights	info:eu-repo/semantics/openAccess
dc.rights.accessrights	info:eu-repo/semantics/openAccess
dc.rights.local	Acceso abierto	spa
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject	Hepatitis Autoinmune
dc.subject	Enfermedades reumatológicas
dc.subject	Perfil inmunoserológico
dc.subject	Frecuencia
dc.subject	Coexistencia
dc.subject.keywords	Autoinmune Hepatitis
dc.subject.keywords	Inmune system diseases
dc.subject.keywords	Autoantibodies
dc.subject.keywords	Prevalence
dc.subject.nlm	WB 115
dc.title	Enfermedades reumatológicas en pacientes con hepatitis autoinmune en un hospital de cuarto nivel de Bogotá entre el 2013 al 2023
dc.title.translated	Reumathologic diseases in patients with autoinmune hepatitis in a fourth level hospital from Bogota, findings between 2013 and 2023
dc.type.coar	https://purl.org/coar/resource_type/c_7a1f
dc.type.coarversion	https://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driver	info:eu-repo/semantics/bachelorThesis
dc.type.hasversion	info:eu-repo/semantics/acceptedVersion
dc.type.local	Tesis/Trabajo de grado - Monografía - Especialización	spa