Capacidad predictiva del Logaritmo de ODDS (LODDS) vs. densidad ganglionar en supervivencia global y libre de recurrencia en cáncer de pene escamocelular

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dc.contributor.advisorDe la hoz, Jose Antonio
dc.contributor.authorAmaya Dueñas, Camilo Andres
dc.contributor.authorPardo Hernández, Luis Felipe
dc.contributor.orcidAmaya Dueñas, Camilo Andres [0009-0001-5950-185X]
dc.contributor.orcidPardo Hernández, Luis Felipe [ 0000-0003-0608-3612]
dc.date.accessioned2024-07-30T13:14:24Z
dc.date.available2024-07-30T13:14:24Z
dc.date.issued2024-07
dc.description.abstractEl carcinoma escamocelular de pene (PSCC) es una malignidad agresiva en donde se ha demostrado que el compromiso ganglionar es el factor pronóstico más importante para predecir supervivencia global (OS) y supervivencia libre de recaída (RFS). En la última década ha surgido el Logaritmo ODDS (LODDS) cómo una herramienta importante para predecir OS y RFS. Se busca definir la utilidad de LODDS cómo herramienta pronóstica en pacientes con PSCC. Estudio retrospectivo que incluyó pacientes con PSCC y compromiso ganglionar, sometidos a linfadenectomía inguinal (ILND) entre el 2007-2021 en el Instituto Nacional de Cancerología. Se incluyeron pacientes ≥18 años, sin otra variante histológica y sin evidencia de enfermedad metastásica. Se realizó análisis de supervivencia para predecir OS y la RFS.
dc.description.abstractenglishPenile squamous cell carcinoma (PSCC) is an aggressive malignancy, where nodal involvement has been shown to be the most important prognostic factor for predicting overall survival (OS). In the last decade, the Log Odds (LODDS) has emerged as an important tool for predicting OS and RFS. The aim is to define the utility of LODDS as a prognostic tool in patients with PSCC. Methods. This is a retrospective and analytical study that included PSCC patients with nodal involvement who underwent inguinal lymphadenectomy (ILND) between 2007-2021 at our institution. Patients ≥18 years, without other histological variants, and without evidence of metastatic disease were included. Survival analysis was performed to predict OS and RFS. Concordance was evaluated using Harrell's C-index.
dc.description.degreelevelEspecializaciónspa
dc.description.degreenameEspecialista en Urologíaspa
dc.description.sponsorshipInstituto Nacional de Cancerologia
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/12762
dc.language.isoes
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.grantorUniversidad El Bosquespa
dc.publisher.programEspecialización en Urologíaspa
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dc.rightsAtribución-NoComercial-CompartirIgual 4.0 Internacional
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.localAcceso abiertospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectCáncer de pene
dc.subjectGanglio linfático
dc.subjectCompromiso extranodal
dc.subjectLinfadenectomía
dc.subject.keywordsPenile Cancer
dc.subject.keywordsLymph Node metastasis
dc.subject.keywordsExtranodal tumour deposit
dc.subject.keywordsLymphadenectomy
dc.subject.nlmWJ100
dc.titleCapacidad predictiva del Logaritmo de ODDS (LODDS) vs. densidad ganglionar en supervivencia global y libre de recurrencia en cáncer de pene escamocelular
dc.title.translatedPredictive Capacity of the logarithm of Odds ( LODDS) vs Lymph Node Density in Overall and Recurrence-Free survival in Penile Squamous Cell Carcinoma
dc.type.coarhttps://purl.org/coar/resource_type/c_7a1f
dc.type.coarversionhttps://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesis/Trabajo de grado - Monografía - Especializaciónspa

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