Resistance in Vancomycin-Resistant Enterococci
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Fecha
2020
Título de la revista
Publicado en
Infectious disease clinics of north america, 1557-9824, Vol. 34, Nro. 4, 2020, p. 751-771
Publicado por
Elsevier
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Título del volumen
Resumen
Descripción
Abstract
Abstract
Serious infections owing to vancomycin-resistant enterococci have historically proven to be difficult clinical cases, requiring combination therapy and management of treatment-related toxicity. Despite the introduction of new antibiotics with activity against vancomycin-resistant enterococci to the therapeutic armamentarium, significant challenges remain. An understanding of the factors driving the emergence of resistance in vancomycin-resistant enterococci, the dynamics of gastrointestinal colonization and microbiota-mediated colonization resistance, and the mechanisms of resistance to the currently available therapeutics will permit clinicians to be better prepared to tackle these challenging hospital-associated pathogens.
Palabras clave
Keywords
VRE, Vancomycin resistant enterococcus, VRE colonization, Colonization resistance, Mechanisms of resistance