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dc.contributor.authorCastro-Rodriguez, Jose A.
dc.contributor.authorRodriguez-Martinez, Carlos E.
dc.contributor.authorSossa-Briceño, Monica P.
dc.date.accessioned2020-08-13T19:43:34Z
dc.date.available2020-08-13T19:43:34Z
dc.identifier.issn1526-0542spa
dc.identifier.urihttp://hdl.handle.net/20.500.12495/3784
dc.description.abstractBronchiolitis is the most common cause of hospitalization among infants during the first 12 months of life, with high direct and indirect cost for health system and families. Different treatment approaches co-exist worldwide resulting in many drugs prescribed, without any proven benefit. Twenty systematic reviews of randomized clinical trials (SRCTs) on management of acute bronchiolitis in children were retrieved through 5 databases and their methodological quality was determined using an AMSTAR tool. Epinephrine showed impact only in short-term outcomes among outpatients (reduced admission at day 1 and improved the clinical score in the first 2 hours, compared to placebo) and inpatients (decreased length of stay (LOS) and improved saturation only in the first 2 hours, compared to nebulized salbutamol, but with high heterogeneity). Nebulized 3% saline among inpatients (but not in the emergency department setting) decreased hospital LOS. In small trials, exogenous surfactant among children may decrease the duration of mechanical ventilation and intensive care unit LOS and had favorable effects on oxygenation and CO2 elimination at 24 hrs. Although several SRCTs are currently available, only few treatments show clinically important improvements. Therefore, it is still difficult to prepare a well-established and accepted guideline for the treatment of acute bronchiolitis.spa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.ispartofseriesPaediatric Respiratory Reviews, 1526-0542, Vol. 16, Nro. 4, 2015, p. 267-275spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S1526054215000032?via%3Dihubspa
dc.titlePrincipal findings of systematic reviews for the management of acute bronchiolitis in childrenspa
dc.type.localArtículo de revista
dc.subject.keywordsAcute bronchiolitis managementspa
dc.subject.keywordsTreatmentspa
dc.subject.keywordsSystematic reviewspa
dc.subject.keywordsMethanalysisspa
dc.identifier.doihttps://doi.org/10.1016/j.prrv.2014.11.004spa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.publisher.journalPaediatric Respiratory Reviewsspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.identifier.instnameinstname:Universidad El Bosque
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.title.translatedPrincipal findings of systematic reviews for the management of acute bronchiolitis in childrenspa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abiertospa
dc.date.issued2015-09


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