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dc.contributor.authorArias, César A.
dc.contributor.authorBeral, Valerie
dc.date.accessioned2020-08-12T18:14:42Z
dc.date.available2020-08-12T18:14:42Z
dc.identifier.issn1740-1534spa
dc.identifier.urihttp://hdl.handle.net/20.500.12495/3769
dc.description.abstractThe genus Enterococcus includes some of the most important nosocomial multidrug-resistant organisms, and these pathogens usually affect patients who are debilitated by other, concurrent illnesses and undergoing prolonged hospitalization. This Review discusses the factors involved in the changing epidemiology of enterococcal infections, with an emphasis on Enterococcus faecium as an emergent and challenging nosocomial problem. The effects of antibiotics on the gut microbiota and on colonization with vancomycin-resistant enterococci are highlighted, including how enterococci benefit from the antibiotic-mediated eradication of Gram-negative members of the gut microbiota. Analyses of enterococcal genomes indicate that there are certain genetic lineages, including an E. faecium clade of ancient origin, with the ability to succeed in the hospital environment, and the possible virulence determinants that are found in these genetic lineages are discussed. Finally, we review the most important mechanisms of resistance to the antibiotics that are used to treat vancomycin-resistant enterococci.spa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherSpringer Naturespa
dc.relation.ispartofseriesNature reviews microbiology, 1740-1534, Vol. 10, Nro. 4, 2012, p. 266-278spa
dc.relation.urihttps://www.nature.com/articles/nrmicro2761spa
dc.titleThe rise of the Enterococcus: Beyond vancomycin resistancespa
dc.type.localArtículo de revista
dc.subject.keywordsAntimicrobial resistancespa
dc.subject.keywordsAntimicrobialsspa
dc.subject.keywordsBacteriaspa
dc.subject.keywordsBacterial pathogenesisspa
dc.subject.keywordsClinical microbiologyspa
dc.identifier.doihttps://doi.org/10.1038/nrmicro2761spa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.publisher.journalNature reviews microbiologyspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.identifier.instnameinstname:Universidad El Bosque
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.title.translatedThe rise of the Enterococcus: Beyond vancomycin resistancespa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abiertospa
dc.date.issued2012-03-16


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