Establishment and multi drug resistance evolution of ST235 Pseudomonas aeruginosa strains in the intensive care unit of a Colombian hospital

Miniatura

Archivos

Martinez_Elena_2014.pdf (245.74 KB)

Fecha

2014

Autores

Título de la revista

Publicado en

Research in Microbiology, 0923-2508, Vol. 165, Nro. 10, 2014, p. 852 - 856

Publicado por

Elsevier Masson

URI

https://hdl.handle.net/20.500.12495/3341

URL de la fuente

https://www.sciencedirect.com/science/article/pii/S0923250814002137

ISSN de la revista

Título del volumen

Resumen

Descripción

Abstract

Drug resistant Pseudomonas aeruginosa represents a therapeutic challenge. To assess the diversity of P. aeruginosa antibiotic resistant variants, isolates were recovered from hospital patients in Colombia. Thirty of 60 isolates contained class 1 integrons and five were of Sequence Type ST235 having appeared in a single intensive care unit. All five possessed an unusual integron but showed differences in gene cassette content and the presence/absence of insertion sequence IS26. This showed that differences can arise rapidly, even within a single ICU. Also, the emergence of IS26 in P. aeruginosa is contributing to the evolution of resistance in this bacterium.

Palabras clave

Keywords

Pseudomonas aeruginosa ST235, IS26, Antibiotic resistance, Hospital acquired infections

Temáticas

Infecciones bacterianas
Farmacorresistencia microbiana
Pseudomonas aeruginosa

Citación

Colecciones

Artículos