Factors associated with dengue virus infection and reinfection in asymptomatic children in two Colombian municipalities

Miniatura

Archivos

Castro-Bonilla, Lorena.pdf (261.16 KB)

Fecha

2018

Autores

Título de la revista

Publicado en

American Journal of Tropical Medicine and Hygiene, 1476-1645, Vol 99, Num 6, 2018, pag 1422-1429

Publicado por

Baltimore

URI

https://hdl.handle.net/20.500.12495/2918

URL de la fuente

https://www.ajtmh.org/content/journals/10.4269/ajtmh.17-0617

ISSN de la revista

Título del volumen

Resumen

Descripción

Abstract

Dengue is the most important arbovirosis in the world. In this study, we assessed the knowledge, attitudes, and practices (KAP) regarding dengue in parents from two small Colombian municipalities in the Cundinamarca Province. Parents and their healthy children from 4 to 14 years of age were included in some public elementary schools. After a medical examination, blood samples were taken for diagnosis of dengue using enzyme-linked immunosorbent assays (capture immunoglobulin M and capture immunoglobulin G [IgG], indirect IgG and detection non-structural viral protein 1) and detection of viral RNA by reverse transcription polymerase chain reaction. In addition, a KAP survey was applied to the children’s parents or tutors. The indirect IgG test determined that of the 347 examined children, 87.9% had a previous infection with the dengue virus (DENV), 12.7% of them were positive for viral RNA (asymptomatic infection), and 32.0% presented reinfections. Risk factors evaluation showed that children aged 8 years and older living in the municipalities for more than 7 years were more likely to be infected or reinfected by DENV. In the same way, poor nutrition, lack of water supply, sewer service, or waste disposal services could raise the likelihood of dengue infections. The surveys indicated that parents have unhealthy practices and a low knowledge about the transmission of the disease, which could result in an increase of mosquito breeding sites, allowing sustained dengue transmission.

Palabras clave

Keywords

Temáticas

Virus del dengue -- Epidemiología
Infecciones asintomáticas
Atributos de enfermedad

Citación

Colecciones

Artículos