First characterization of a cluster of VanA-Type glycopeptide-resistant Enterococcus faecium, Colombia

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Fecha

2015

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Publicado en

Emerging Infectious Diseases, 1080-6040, Vol.8, Nro.9, 2015, p.961–965

Publicado por

Centers for Disease Control and Prevention

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Abstract

From August 1998 to October 1999, glycopeptide-resistant enterococci (GRE) were isolated from 23 infected patients at a teaching hospital in Medellín, Colombia. Identification at the species level and by multiplex polymerase chain reaction assay indicated that all isolates were Enterococcus faecium. The isolates were highly resistant to ampicillin, ciprofloxacin, gentamicin, penicillin, streptomycin, teicoplanin, and vancomycin; they were susceptible only to chloramphenicol, linezolid, and nitrofurantoin. Determination of glycopeptide genotype indicated the presence of the vanA gene in all isolates. Molecular typing by pulsed field gel electrophoresis showed that all isolates were closely related. This study is the first molecular characterization of GRE in Colombia.

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Keywords

Vancomycin, Enterococci, Resistance, Glycopeptide-resistant enterococci

Temáticas

Sistema urinario
Enterococcus faecalis
Infección hospitalaria

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