A considerable number of patients with coronary syndrome enter the cardiovascular rehabilitation program with severe periodontal disease which continues to advance in most cases. Periodontal treatment is considered low-risk but there could be localized trauma which could induce gingival tissue bleeding due to the platelet anti-aggregant effect, which led to the development of an educational tool on the relation between periodontitis and coronary syndrome in order to provide support for the periodontal programs for this type of patients. To design and develop an instructive for patients with coronary syndrome who attend the Fundacion Clinica Shaio, regarding said syndrome and periodontal disease which will contribute to prevent haemorrhaging in patients undergoing periodontal treatment. A theoretical frame was developed based on current scientific evidence; afterwards, a conceptual clinical approach was taken and an accessible instructive with images associated with the text for better understanding was designed. This was done with Adobe InDesign and once this stage was completed, a team of experts went to the Fundacion Clinica Shaio in order to validate the instrument. The group of experts reviewed the instructive, including text, content, graphics and printing fonts which will be handed out to the patients attending cardiovascular rehabilitation in the mentioned centre.