Scabies herpeticum, an emerging clinical form of crusted scabies in AIDS patient: case report and literature review
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2018
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International journal of dermatology, 1365-4632, Vol. 58, Nro. 10, 2018
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Wiley-Blackwell
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Abstract
Scabies is a cutaneous ectoparasitosis caused by the mite,
Sarcoptes scabiei variety hominis, which affects 130 million
people worldwide every year. The risk factors include:
overcrowded conditions, extended-care facilities, child care,
and immunosuppressive conditions such as systemic immunosuppressive therapy, elderly, Down syndrome, mental disorders, malignant neoplasms, connective tissue diseases,
metabolic disorders, leprosy, lymphotropic virus type 1, and
acquired immunodeficiency syndrome (AIDS). As for the
transmission, it usually occurs through direct skin-to-skin contact (sexual intercourse and other sexual behaviors with an
infected sexual partner) and fomites such as infested bedding
or clothing.
Three types of scabies are clinically distinguished: classic
scabies, nodular scabies, and crusted scabies (CS); the latter is
the rarest presentation of this disease so far in which the failure
of the cellular immune system of the host generates a super
infestation of mites, which results in a great inflammatory reaction and secondary epidermal hyperkeratosis
Crusted scabies represents a clinical challenge, because it can
present with a severe and atypical course in immunosuppressed
patients. Additionally, superposition with a simultaneous infection in the same site can generate diagnostic confusion, inadequate treatments, and risk of secondary irreversible sequelae
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Temáticas
Síndrome de inmunodeficiencia adquirida
Herpes simple
Terapia antirretroviral altamente activa
Herpes simple
Terapia antirretroviral altamente activa