Simultaneous infection with enterobacteriaceae and pseudomonas aeruginosa harboring multiple carbapenemases in a returning traveler colonized with candida auris

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Fecha

2020

Título de la revista

Publicado en

American Society for Microbiology Journals,1098-6596, Vol.64, Nro. 2, 2020, p. 1-6

Publicado por

American Society for Microbiology

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Descripción

Abstract

We report our clinical experience treating a critically ill patient with polymicrobial infections due to multidrug-resistant Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa in a 56-year-old woman who received health care in India and was also colonized by Candida auris. A precision medicine approach using whole-genome sequencing revealed a multiplicity of mobile elements associated with NDM-1, NDM-5, and OXA-181 and, supplemented with susceptibility testing, guided the selection of rational antimicrobial therapy.

Palabras clave

Keywords

Candida auris, Enterobacteriaceae, Pseudomonas aeruginosa, Carbapenemase

Temáticas

Infecciones bacterianas
Análisis de secuencia de ADN
Resistencia a medicamentos

Citación

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