Now showing items 1-4 of 4
Transferable Vancomycin resistance in a community-associated mrsa lineagetransferable vancomycin resistance in a community-associated MRSA lineage
(Massachusetts Medical Society, 2014-04-17)
We report the case of a patient from Brazil with a bloodstream infection caused by a strain of methicillin-resistant Staphylococcus aureus (MRSA) that was susceptible to vancomycin (designated BR-VSSA) but that acquired ...
Whole-genome analyses of enterococcus faecium isolates with diverse daptomycin MICs
(American Society for Microbiology, 2014-08)
Daptomycin (DAP) is a lipopeptide antibiotic frequently used as a "last-resort" antibiotic against vancomycin-resistant Enterococcus faecium (VRE). However, an important limitation for DAP therapy against VRE is the emergence ...
Disrupting membrane adaptation restores in vivo efficacy of antibiotics against multidrug-resistant enterococci and potentiates killing by human neutrophils
(Oxford University Press, 2019)
Daptomycin resistance in enterococci is often mediated by the LiaFSR system, which orchestrates the cell membrane stress response. Activation of LiaFSR through the response regulator LiaR generates major changes in cell ...
Daptomycin dose-ranging evaluation with single-dose versus multidose ceftriaxone combinations against streptococcus mitis/ oralis in an ex vivo simulated endocarditis vegetation model
(American Society for Microbiology, 2019)
T The viridans group streptococci (VGS) are a heterogeneous group of organisms which are important components of the normal human oral flora. Among the VGS, the Streptococcus mitis/oralis subgroup is one of the most common ...