Now showing items 1-3 of 3
Disrupting membrane adaptation restores in vivo efficacy of antibiotics against multidrug-resistant enterococci and potentiates killing by human neutrophils
(Oxford University Press, 2019)
Daptomycin resistance in enterococci is often mediated by the LiaFSR system, which orchestrates the cell membrane stress response. Activation of LiaFSR through the response regulator LiaR generates major changes in cell ...
LiaR‐independent pathways to daptomycin resistance in enterococcus faecalis reveal a multilayer defense against cell envelope antibiotics
The lipopeptide antibiotic daptomycin (DAP) is a key drug against serious enterococcal infections, but the emergence of resistance in the clinical setting is a major concern. The LiaFSR system plays a prominent role in the ...
Environment shapes the accessible daptomycin resistance mechanisms in enterococcus faecium
(American Society for Microbiology, 2019)