Now showing items 743-762 of 1716

    • G-quadruplex ligands:potent inhibitors of telomerase activity and cell proliferation in plasmodium falciparum 

      Calvo, Eliana; Wasserman, M.
      Telomeres are DNA and protein structures located at the ends of eukaryotic chromosomes. These structures maintain chromosomal stability by impeding chromosomal ends from being recognized and processed as fragmented DNA. ...
    • GALILEO: A georeferenced system proposed for emergency services’ population control 

      Cruz, Andres; Ospina Gomez, Sebastian; Feijóo García, Pedro Guillermo
      Introducción: La saturación y sobrepoblación en los centros de urgencias es un problema que se presenta a nivel global y, aunque se ha abordado desde diferentes disciplinas y perspectivas, todavía afecta a ciudadanos que ...
    • GALILEO: Emergency rooms and crowd computing 

      Cruz, Andrés F.; Ospina, Sebastián; Feijóo-García, Pedro Guillermo; Suarez, Daniel R.
      This research and software development project, is carried out based on a problem about the clinical context in Bogotá D.C., Colombia. It seeks through a web and mobile application, to inform citizens who are looking for, ...
    • GASIM: the gate array graphical simulator for FPGA architecture learning 

      de Castro Cuevas, Osberth Cristhian; Murrugarra Quiroz, Cecilia
      Field Programmable Gate Arrays, also called FPGA, are the main contemporary tool for digital systems learning and development. Its benefits are more than evident, but also are its internal complexity. The widespread use ...
    • Gastrointestinal symptoms and elevated levels of anti- saccharomyces cerevisiae antibodies are associated with higher disease activity in Colombian patients with spondyloarthritis 

      Romero-Sánchez, Consuelo; Parra, Viviana; De Avila, Juliette; Rueda, Juan Camilo; Londoño, John Darío; Valle-Oñate, Rafael; Bautista-Molano, Wilson Armando; Bello-Gualtero, Juan M.
      Background. Spondyloarthritis (SpA) is a group of articular inflammatory rheumatic diseases that their gastrointestinal manifestations are around 10% of their extra-articular symptoms, supporting that the inflammatory ...
    • Gastrostomía endoscópica percutánea asistida por laparoscopia: reporte de caso 

      Pinilla Morales, Raúl Eduardo; Hernández Restrepo, Juan David
      La gastrostomía endoscópica percutánea (GEP) es la técnica de elección para instaurar una vía de alimentación en pacientes que requieren soporte nutricional especial por más de 4 semanas; sin embargo, por ser una intervención ...
    • Genetic basis for in vivo daptomycin resistance in enterococci 

      Arias, Cesar A.; Panesso, Diana; McGrath, Danielle M.; Qin, Xiang; Mojica, María Fernanda; Miller, Corwin; Diaz, Lorena; Tran, Truc T.; Rincon Núñez, Sandra; Reyes, Jinnethe; Roh, Jung H.; Lobos, Elizabeth; Sodergren, Erica; Pasqualini, Renata; Arap, Wadih; Quinn, John P.; Shamoo, Yousif; Murray, Barbara E.; Weinstock, George M.
      Daptomycin is a lipopeptide with bactericidal activity that acts on the cell membrane of enterococci and is often used off-label to treat patients infected with vancomycin-resistant enterococci. However, the emergence of ...
    • Genome plasticity favours double chromosomal Tn4401b-blaKPC-2 transposon insertion in the Pseudomonas aeruginosa ST235 clone 

      Castellanos, Jaime; Abril Riaño, Deisy Julieth; Moncayo-Ortiz, José Ignacio; Corredor Rozo, Zayda Lorena; Reyes, Niradiz; Tovar, Catalina; Sánchez, Héctor Fabio; Guaca-González, Yina Marcela; Llanos-Uribe, Carmen Elisa; Olarte, Narda María; Vanegas, Natasha; Escobar-Pérez, Javier; Castro Cardozo, Betsy Esperanza; Marquez-Ortiz, Ricaurte Alejandro
      Background Pseudomonas aeruginosa Sequence Type 235 is a clone that possesses an extraordinary ability to acquire mobile genetic elements and has been associated with the spread of resistance genes, including genes that ...
    • Genomic analysis of ctx-m-group-1-producing extraintestinal pathogenic e. Coli (expec) from patients with urinary tract infections (uti) from colombia 

      de la Cadena, Elsa; Mojica, María Fernanda; Castillo, Nathaly; Correa, Adriana M.; Appel, Tobias Manuel; Gutiérrez Betancur, Juan Carlos; Pallares, Christian José; Villegas, María Virginia
      Background: The dissemination of the uropathogenic O25b-ST131Escherichia coliclone constitutes a threat to public health. We aimed to determine the circulation ofE. colistrains belonging to ...
    • Genomic analysis of head and neck cancer cases from two high incidence regions 

      Perdomo Lara, Sandra Janneth; Anantharaman, Devasena; Foll, Matthieu; Durand, Geoffroy; Abedi-Ardekani, Behnoush; Reis Rosa, Luciana Albina; Holmila, Reetta; Le Calvez-Kelm, Florence; Tajara, Eloiza H.; Wünsch-Filho, Victor; Levi, José Eduardo; Vilensky, Marta; Polesel, Jerry; Holcatova, Ivana; Simonato, Lorenzo; Canova, Cristina; Lagiou, Pagona; Brennan, Paul; McKay, James D.
      We investigated how somatic changes in HNSCC interact with environmental and host risk factors and whether they influence the risk of HNSCC occurrence and outcome. 180-paired samples diagnosed as HNSCC in two high incidence ...
    • Genomic and epidemiological evidence of a dominant panton-valentine leucocidin-positive methicillin resistant staphylococcus aureus lineage in Sri Lanka and presence among isolates from the United Kingdom and Australia 

      McTavish, Sharla M.; Snow, Sarah J.; Cook, Ellie C.; Pichon, Bruno; Coleman, Sarah; Coombs, Geoffrey W.; Pang, Stanley; Arias, César A.; Díaz, Lorena; Boldock, Emma; Davies, Steve; Udukala, Mangala; Kearns, Angela Marie; Siribaddana, Sisira; De Silva, Thushan I.
      Objective: To undertake the first detailed genomic analysis of methicillin-resistant Staphylococcus aureus (MRSA) isolated in Sri Lanka. Methods: A prospective observational study was performed on 94 MRSA isolates collected ...
    • Genomic and molecular characterization of clinical isolates of Enterobacteriaceae harboring mcr-1 in Colombia, 2002 to 2016 

      Saavedra, Sandra Yamile; Diaz, Lorena; Wiesner, Magdalena; Arévalo, Stefany Alejandra; Correa, Adriana; Reyes, Jinnethe; Hidalgo, Andrea Melissa; de la Cadena, Elsa; Perenguez, Marcela Nataly; Montaño, Lucy Angeline; Ardila, Javier; Ríos, Rafael; Ovalle, María Victoria; Díaz, Paula; Porras, Paola; Villegas, Maria V.; Arias, Cesar A; Beltrán, mauricio; Duarte, Carolina
      Polymyxins are last-resort antimicrobial agents used to treat infections caused by carbapenem-resistant Enterobacteriaceae. Due to the worldwide dissemination of polymyxin resistance in animal and human isolates, we aimed ...
    • Genomic diversity of burkholderia pseudomalleiIsolates, Colombia 

      Duarte, Carolina; Montúfar, Franco E.; Moreno, Jaime Enrique; Sánchez, Dora; Rodríguez, José Y.; Torres, Alfredo Gabriel; Morales, Soraya; Bautista, Adriana; Huertas, Mónica G.; Gulvik, Christopher A.; Elrod, Mindy Glass; Blaney, David D.; Gee, Jay E. (Centers for Disease Control and Prevention (CDC), 2021-02)
      We report an analysis of the genomic diversity of isolates of Burkholderia pseudomallei, the cause of melioidosis, recovered in Colombia from routine surveillance during 2016–2017. B. pseudomallei appears genetically ...
    • Genomic epidemiology of NDM-1-Encoding Plasmids in latin american clinical isolates reveals insights into the evolution of multidrug resistance 

      Castellanos, Jaime; Haggerty, Leanne; Olarte, Narda María; Garza-Ramos, Ulises; Silva-Sanchez, Jesus; Castro Cardozo, Betsy Esperanza; Valderrama, Ismael Alberto; Charles, Ian G.; Vanegas, Natasha; Escobar-Pérez, Javier Antonio; Marquez-Ortiz, Ricaurte Alejandro; Duarte, Carolina; Sim, Eby M.; Beltran, Mauricio; Moncada, Maria Victoria; Petty, Nicola K.
      Bacteria that produce the broad-spectrum Carbapenem antibiotic New Delhi Metallo-β-lactamase (NDM) place a burden on health care systems worldwide, due to the limited treatment options for infections caused by them and the ...
    • Genomic epidemiology of vancomycin-resistant enterococcus faecium (VREfm) in Latin America: revisiting the global VRE population structure 

      Rios, Rafael; Reyes, Jinnethe; Carvajal Ortiz, Lina Paola; Rincon Núñez, Sandra; panesso, diana; Dinh, An Q.; Kolokotronis, Sergios-Orestis; Narechania, Apurva; Tran, Truc T.; Munita, Jose M.; Murray, Barbara E; Planet, Paul J.; Arias, Cesar A.; Diaz, Lorena
      Little is known about the population structure of vancomycin-resistant Enterococcus faecium (VREfm) in Latin America (LATAM). Here, we provide a complete genomic characterization of 55 representative Latin American VREfm ...
    • Genotypic characterization of Porphyromonas gingivalis isolated from subgingival plaque and blood sample in positive bacteremia subjects with periodontitis 

      Pérez‐Chaparro, P. Juliana; Gracieux, Patrice; Lafaurie, Gloria Ines; Donnio, Pierre‐Yves; Bonnaure‐Mallet, Martine
      The objective of this study was to investigate clonal relationship among Porphyromonas gingivalis isolated from subgingival plaque and blood samples in positive transient bacteremia subjects with periodontitis. Unrelated ...
    • Genotyping low-grade gliomas among Hispanics 

      Cardona-Mendoza, Andrés Felipe; Rojas, Leonardo; Wills, Beatriz; Behaine, José; Jiménez, Enrique; Hakim, Fernando; Useche, Nicolás; Bermúdez, Sonia; Arrieta, Oscar; Mejía, Juan Armando; Ramón, Juan Fernando; Carranza, Hernán; Vargas, Carlos; Otero, Jorge; González, Diego; Rodríguez, July; Ortiz, León Darío; Cifuentes, Hernando; Balaña, Carmen
      Low-grade gliomas (LGGs) are classified by the World Health Organization as astrocytoma (DA), oligodendroglioma (OD), and mixed oligoastrocytoma (OA). TP53 mutation and 1p19q codeletion are the most-commonly documented ...
    • Genotyping of fusarium isolates from onychomycoses in Colombia: detection of two new species within the fusarium solani species complex and in vitro antifungal susceptibility testing 

      Guevara-Suarez, Marcela; Cepero de García, María Caridad; De Bedout, Catalina; García, Ana María; Amézquita, Adolfo; Espinel-Ingroff, Ana; Restrepo, Silvia; Celis, Adriana
      Fusariosis have been increasing in Colombia in recent years, but its epidemiology is poorly known. We have morphologically and molecularly characterized 89 isolates of Fusarium obtained between 2010 and 2012 in the cities ...
    • Genotyping squamous cell lung carcinoma in Colombia (Geno1.1-CLICaP) 

      Cardona-Mendoza, Andrés Felipe; Ruiz-Patinõ, Alejandro; Arrieta, Oscar; Ricaurte, Luisa María; Zatarain-Barrón, Zyanya Lucia; Rodríguez, July; Avila, Jenny; Rojas, Leonardo L.; Recondo, Gonzalo; Barrón-Barrón, Feliciano; Archila, Pilar; Sotelo, Carolina; Bravo Espinosa, Melissa Andrea; Zamudio, Nataly; Corrales, Luis; Martín, Claudio Marcelo; Rolfo, Christian; Viola, Lucia; Carranza, Hernán; Vargas, Carlos Alberto; Otero, Jorge Miguel; Bermudez Diaz, Maritza Alejandra; Gamez, Tatiana; Pino, Luis Eduardo; Rosell, Rafael Costa
      Background: Lung cancer is a public health problem, and squamous cell carcinoma (SCC) is the second most prevalent subtype of this neoplasm. Compared to other subtypes, including adenocarcinoma, SCC is less well understood ...