Examinando por Autor "Otero, Jorge Miguel"

Mostrando 1 - 5 de 5
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    Antibiotics impair immune checkpoint inhibitor effectiveness in hispanic patients with non-small cell lung cancer (AB-CLICaP)
    (Wiley-Blackwell) Ruiz-Patinõ, Alejandro; Barrón-Barrón, Feliciano; Cardona-Mendoza, Andrés Felipe; Corrales, Luis; Mas, Luis; Martín, Claudio Marcelo; Zatarain-Barrón, Zyanya Lucia; Recondo, Gonzalo; Ricaurte, Luisa María; Rojas Puentes, Leonardo; Archila, Pilar; Rodríguez, July F.; Sotelo-Rodríguez, Diana Carolina; Viola Muñoz, Lucía; Vargas Báez, Carlos Alberto; Carranza, Hernán; Otero, Jorge Miguel; Pino, Luis Eduardo; Rolfo, Christian; Rosell, Rafael Costa; Arrieta, Oscar; Cardona-Mendoza, Andrés Felipe [0000-0002-6697-5471]; Vargas Báez, Carlos Alberto [0000-0002-6076-8260]; Rojas Puentes, Leonardo [0000-0002-7865-5424]; Sotelo-Rodríguez, Diana Carolina [0000-0002-7763-4760]; Viola Muñoz, Lucía [0000-0002-1647-2884]
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    Genotyping squamous cell lung carcinoma in Colombia (Geno1.1-CLICaP)
    (Frontiers Media S.A.) Cardona-Mendoza, Andrés Felipe; Ruiz-Patinõ, Alejandro; Arrieta, Oscar; Ricaurte, Luisa María; Zatarain-Barrón, Zyanya Lucia; Rodríguez Ariza, July Katherine; Ávila Coy, Jenny Mireya; Rojas Puentes, Leonardo; Recondo, Gonzalo; Barrón-Barrón, Feliciano; Archila, Pilar; Sotelo-Rodríguez, Diana Carolina; Bravo Espinosa, Melissa Andrea; Zamudio, Nataly; Corrales, Luis; Martín, Claudio Marcelo; Rolfo, Christian; Viola Muñoz, Lucía; Carranza, Hernán; Vargas Báez, Carlos Alberto; Otero, Jorge Miguel; Bermúdez Díaz, Maritza Alejandra; Gamez, Tatiana; Pino, Luis Eduardo; Rosell, Rafael Costa; Cardona-Mendoza, Andrés Felipe [0000-0002-6697-5471]; Vargas Báez, Carlos Alberto [0000-0002-6076-8260]; Rojas Puentes, Leonardo [0000-0002-7865-5424]; Rodríguez Ariza, July Katherine [0000-0003-1168-595X]; Sotelo-Rodríguez, Diana Carolina [0000-0002-7763-4760]; Ávila Coy, Jenny Mireya [0000-0002-2968-7980]; Bermúdez Díaz, Maritza Alejandra [0000-0002-5870-0136]; Viola Muñoz, Lucía [0000-0002-1647-2884]
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    Immunotherapy at any line of treatment improves survival in patients with advanced metastatic non‐small cell lung cancer (NSCLC) compared with chemotherapy (Quijote‐CLICaP)
    (Wiley-Blackwell, 2020) Ruiz-Patinõ, Alejandro; Arrieta, Oscar; Cardona-Mendoza, Andrés Felipe; Martín, Claudio Marcelo; Raez, Luis Estuardo; Zatarain-Barrón, Zyanya Lucia; Barron, Feliciano; Ricaurte, Luisa María; Bravo-Garzón, María A.; Mas, Luis A.; Corrales, Luis; Rojas Puentes, Leonardo; Lupinacci, Lorena; Perazzo, Florencia; Bas, Carlos Arturo; Carranza, Omar E.; Puparelli, Carmen; Rizzo, Miguel M; Ruiz, Rossana; Rolfo, Christian; Archila, Pilar; Rodríguez, July F.; Vargas Báez, Carlos Alberto; Carranza, Hernán; Otero, Jorge Miguel; Pino, Luis Eduardo; Ortíz, Carlos; Laguado, Paola; Rosell, Rafael Costa; Cardona-Mendoza, Andrés Felipe [0000-0002-6697-5471]; Vargas Báez, Carlos Alberto [0000-0002-6076-8260]; Rojas Puentes, Leonardo [0000-0002-7865-5424]
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    p.G12C KRAS mutation prevalence in non-small cell lung cancer: Contribution from interregional variability and population substructures among Hispanics
    (Neoplasia Press, Inc., 2022-01) Ruíz-Patiño, Alejandro; Rodríguez, July; Ávila, Jenny; Archila, Pilar; Carranza, Hernán; Vargas, Carlos Alberto; Otero, Jorge Miguel; Arrieta, Oscar; Zatarain-Barrón, Lucia; Sotelo, Carolina; Ordoñez, Camila; Cardona, Andrés Felipe [https://orcid.org/0000-0003-3525-4126]
    Antecedentes: El exón 2 de KRAS p. La mutación G12C en pacientes con adenocarcinoma de pulmón ha ido aumentando en relevancia debido al desarrollo y la eficacia de nuevos medicamentos de tratamiento. Estudios en diferentes poblaciones indican que la variabilidad regional entre etnias y ascendencias podría desempeñar un papel fundamental en el desarrollo de esta alteración molecular dentro del cáncer de pulmón. Results: Included were 979 patients with a national mean frequency for the KRAS exon 2 p.G12C mutation of 7.97% (95%CI 6.27-9.66%). Variation between regions was also identified with Antioquia reaching a positivity value of 12.7% (95%CI 9.1-16.3%) in contrast to other regions such as Bogota DC (Capital region) with 5.4% (2.7-8.2%) and Bolivar with 2.4% (95%CI 0-7.2%) (p-value = 0.00262). Furthermore, Short tandem repeat population substructures were found for eight markers that strongly yielded association with KRAS exon 2 p.G12C frequency reaching an adjusted R2 of 0.945 and a p-value of < 0.0001. Conclusions: Widespread identification of KRAS exon 2 p.G12C mutations, especially in cases where NGS is not easily achieved is feasible at a population based level that can characterize regional and national patterns of mutation status. Furthermore, this type of mutation prevalence follows a population substructure pattern that can be easily determined by population and ancestral markers such as STR.
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    Scientific publications in cancer: in Latin America, strong scientific networks increase productivity (the TENJIN study)
    (Elsevier, 2020) Ruiz-Patinõ, Alejandro; Cardona-Mendoza, Andrés Felipe; Arrieta, Oscar; Rolfo, Christian; Gomez, Henry; Raez, Luis Estuardo; Lopes, Gilberto De Lima; Zatarain-Barrón, Zyanya Lucia; Ricaurte, Luisa María; Zamudio-Molano, Nataly; Rangel, Valentina; Oviedo, Juan; Solano, Maria Paula; Rojas Puentes, Leonardo; Corrales, Luis; Martín, Claudio Marcelo; Mas, Luis; Cuello, Mauricio; Barrón-Barrón, Feliciano; Otero, Jorge Miguel; Carranza, Hernán; Vargas Báez, Carlos Alberto; Rosell, Rafael Costa; Cardona-Mendoza, Andrés Felipe [0000-0002-6697-5471]; Vargas Báez, Carlos Alberto [0000-0002-6076-8260]; Rojas Puentes, Leonardo [0000-0002-7865-5424]