Predictors for the prescription of albuterol in infants hospitalized for viral bronchiolitis

dc.contributor.authorPiña-Hincapie, Sol Maria
dc.contributor.authorSossa-Briceño, Mónica P.
dc.contributor.authorRodríguez-Martínez, Carlos E.
dc.date.accessioned2020-04-26T20:58:05Z
dc.date.available2020-04-26T20:58:05Z
dc.date.issued2020
dc.description.abstractenglishIntroduction and Objectives Despite the recommendation against routine use of inhaled bronchodilators in infants with viral bronchiolitis given in the main clinical practice guidelines (CPGs) on viral bronchiolitis, albuterol is widely prescribed to patients with this disease. The aim of this study was to identify predictors of prescription of albuterol in a population of infants hospitalized for viral bronchiolitis. Material and Methods An analytical cross-sectional study performed during the period from March 2014 to August 2015, in a random sample of patients <2 years old hospitalized in the Fundacion Hospital La Misericordia, a hospital located in Bogota, Colombia. After reviewing the electronic medical records, we collected demographic, clinical, and disease-related information, including prescription of albuterol at any time during the course of hospitalization as the outcome variable. Results For a total of 1365 study participants, 1042 (76.3%) were prescribed with albuterol therapy. After controlling for potential confounders, it was found that age (OR 1.11; CI 95% 1.08–1.15; p < 0.001), and a prolonged length of stay (LOS) (OR 1.93; CI 95% 1.44–2.60; p < 0.001) were independent predictors of prescription of albuterol in our sample of patients. By contrast, albuterol prescription was less likely in the post-guideline assessment period (OR 0.41; CI 95% 0.31–0.54; p < 0.001), and in infants with RSV isolation (OR 0.71; CI 95% 0.52–0.97; p = 0.035). Conclusions Albuterol was highly prescribed in our population of inpatients with the disease. The independent predictors of prescription of albuterol in our sample of patients were age, implementation of a CPG on viral bronchiolitis, RSV isolation, and LOS.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.aller.2019.10.007
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn0301-0546
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2400
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalAllergologia et immunopathologiaspa
dc.relation.ispartofseriesAllergologia et immunopathologia, 0301-0546, 2020spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0301054620300410
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf256
dc.rights.creativecommons2020
dc.rights.localAcceso cerradospa
dc.subject.decsCalidad de la atención de saludspa
dc.subject.decsAnálisis de datosspa
dc.subject.decsNiñospa
dc.subject.keywordsAlbuterolspa
dc.subject.keywordsBronchiolitisspa
dc.subject.keywordsClinical practice variationsspa
dc.titlePredictors for the prescription of albuterol in infants hospitalized for viral bronchiolitisspa
dc.title.translatedPredictors for the prescription of albuterol in infants hospitalized for viral bronchiolitis
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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