Viability and effects on bacterial proteins by oral rinses with hypochlorous acid as active ingredient

dc.contributor.authorCastillo, Diana M.
dc.contributor.authorCastillo, Yormaris
dc.contributor.authorJola, Johana
dc.contributor.authorCalderón, Justo Leonardo
dc.contributor.authorDelgadillo, Nathaly Andrea
dc.contributor.authorNeuta, Yineth
dc.contributor.authorLafaurie, Gloria Ines
dc.contributor.orcidLafaurie, Gloria Ines [0000-0003-3986-0625]
dc.contributor.orcidDelgadillo, Nathaly Andrea [0000-0001-8842-549X]
dc.date.accessioned2019-07-31T18:49:07Z
dc.date.available2019-07-31T18:49:07Z
dc.date.issued2015
dc.description.abstractenglishThis study investigated the effect of hypochlorous acid (HOCl) rinses and chlorhexidine (CHX) on the bacterial viability of S. mutans, A. israelii, P. gingivalis, A. actinomycetemcomitans, E. corrodens, C. rectus, K. oxytoca, K. pneumoniae and E. cloacae. The percentage of live bacteria was tested by fluorescence method using Live/Dead kit(r) and BacLight (Molecular Probes(r)) and compared between groups by the Kruskal-Wallis and U Mann-Whitney tests with Bonferroni correction (p value<0.012). The effect of HOCl and CHX on total proteins of P. gingivalis and S. mutans was determined by SDS-PAGE. CHX showed a higher efficacy than HOCl against S. mutans, A. israelii, E. corrodens and E. cloacae (p<0.001) while HOCl was more effective than CHX against P. gingivalis, A. actinomycetemcomitans, C. rectus and K. oxytoca (p=0.001). CHX and HOCl had similar efficacy against K. pneumoniae. Proteins of P. gingivalis and S. mutans were affected similarly by HOCl and CHX. HOCl reduced the bacterial viability especially in periodontopathic bacteria, which may support its use in the control of subgingival biofilm in periodontal patients.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://dx.doi.org/10.1590/0103-6440201300388
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1806-4760
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/1579
dc.language.isoeng
dc.publisherFundação Odontológica de Ribeirão Pretospa
dc.publisher.journalBrazilian Dental Journalspa
dc.relation.ispartofseriesBrazilian Dental Journal, 1806-4760, Vol. 26, Num. 5, 2015spa
dc.relation.urihttps://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402015000500519&lng=en&nrm=iso&tlng=en
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf369
dc.rights.creativecommons2015
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.decsStreptococcus mutansspa
dc.subject.decsProteobacteriaspa
dc.subject.decsÁcido hipoclorosospa
dc.subject.keywordsHypochlorous acidspa
dc.subject.keywordsChlorhexidinespa
dc.subject.keywordsBacterial viabilityspa
dc.titleViability and effects on bacterial proteins by oral rinses with hypochlorous acid as active ingredientspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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